The ABI3BP Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ABI3BP. This antibody recognizes Human antigen. The ABI3BP Antibody has been validated for the following applications: Immunohistochemistry.
Description
A target of NESH-SH3/Abi3bp (TARSH) was originally identified as an SH3 domain-binding molecule of the NESH-SH3/Abi3 protein that is involved in Rac-dependent actin polymerization. In recent studies, TARSH gene expression was dramatically induced in mouse embryonic fibroblasts (MEFs) replicative senescence and suppressed in human lung carcinoma specimens and thyroid carcinomas. However, the molecular mechanism underlying the regulation of TARSH in tumorigenesis remains unclear